Pharmacy
Overview
SRRSH’s Department of Pharmacy, was established on January 9, 1993. After more than 30 years of development, it has grown into a nationally renowned pharmacy center that integrates pharmaceutical services, scientific research, and teaching. In drug management, adhering to the concept of safe medication, it fully utilizes information technology to achieve closed-loop management from drug storage to patient medication. In pharmaceutical services, it leads the country in several innovative initiatives, including outpatient non-infusion, comprehensive prescription review, PIVAS, personalized patient medication management, and mobile smart pharmacists. In teaching and research, the department has established 2 national clinical pharmacist training bases and 1 provincial pretrial center pharmacist training base, participated in the establishment of the Zhejiang University Clinical Pharmacy Research Center, and engaged in exchanges and cooperation with many domestic and international medical institutions. The Department of Pharmacy is committed to building a high-level, high-quality, and efficient pharmacy team, making positive contributions to the development of the hospital and social progress. Currently, the department has 1 postdoctoral fellow, 8 PhDs, more than 70 master's degree holders, and 7 master's supervisors. In recent years, the department’s influence has rapidly increased, and it has been nominated twice in the Fudan University Rankings for the East China region.
Technical advantages
The Department of Pharmacy has a comprehensive pharmaceutical management system, which includes multiple pharmaceutical management and service departments such as the drug warehouse, pretrial center, various dispensing departments, quality management, and clinical pharmacy. These departments provide pharmaceutical technical support to the hospital and are responsible for all drug-related affairs. To better manage and coordinate drug therapy, the hospital has organized several specialized management teams under the Pharmaceutical Management and Therapeutics Committee, such as the Antimicrobial Management Team, Antineoplastic Drug Management Team, and Glucocorticoid Application Management Team. These teams, under the guidance of the committee, work together with the Department of Pharmacy to ensure rational drug use in the hospital.
In terms of drug management, the Department of Pharmacy always adheres to the concept of rational drug use, continuously improving systems, optimizing processes, and fully promoting informatization and automation to improve quality and efficiency. Outpatient and emergency prescriptions, external prescriptions, and inpatient prescriptions undergo comprehensive prescription review and intelligent monitoring and control (this project won the highest award "Excellence in Practice Award" at the 4th Public Hospital Performance Conference). The department conducts multi-dimensional reviews and controls on key monitored drugs, special drugs, top-cost drugs, and abnormal use drugs, linking patient medication with clinical indicators such as laboratory reports, firmly establishing a firewall for safe medication. Through comprehensive measures, the hospital's drug proportion has remained at a relatively low level nationwide for many years, and the pharmacy-related indicators in the performance evaluation of tertiary public hospitals, including the intensity of antimicrobial use and the growth rate of per capita drug costs for outpatient and inpatient services, have received full marks since the evaluation began.
In terms of pharmaceutical services, the Department of Pharmacy is a national leader. (1) In clinical pharmacy, clinical pharmacists have been serving patients using the "resident clinical pharmacist" model for many years, aiming to be closer to patients and clinical practice. Utilizing the mobile "Clinical Pharmacy Information System" and the MTM management model, they carry out pharmaceutical rounds, pharmaceutical monitoring, and medication follow-up, achieving bedside pharmaceutical services and improving patient medication safety. The department has built the LUNGTOX network (the first in China and the second in the world) to improve safe medication for the lungs, providing references for clinical medication and monitoring (this project won the highest award "Excellence in Practice Award" at the 3rd Public Hospital Performance Conference). At the same time, the department has established multiple independent/joint pharmacy clinics, actively engaging in patient education and chronic disease management. With the advancement of new pharmaceutical service concepts, clinical pharmacists conduct research on the pharmacokinetics/pharmacodynamics of antimicrobial drugs and therapeutic drug monitoring (TDM), achieving the translation of precise pharmaceutical research into clinical practice. They also use pharmacoeconomics and comprehensive drug evaluation methods to conduct clinical treatment plan evaluations based on big data and evidence-based approaches. (2) In dispensing services, the Department of Pharmacy was the first in the country to implement outpatient non-infusion and lead the reform of traditional dispensing models. It was the first in the country to run PIVAS, ensuring drug and healthcare safety. The department promotes the "all-in-one" concept of total parenteral nutrition (TPN) and advances the rational use of TPN. It was the first in the country to explore prescription review and is one of the first medical institutions to implement comprehensive prescription review. Additionally, it actively promotes the construction of smart pharmacies, optimizing outpatient pharmaceutical services and achieving the transformation from automation to intelligence: ① The "SRRSH Smart Pharmacist" service platform ensures medication timeliness, accuracy, and convenience for patients, effectively ensuring the medication safety of discharged patients (this platform has been awarded the Top Ten Innovation Projects in the 2019 China Pharmaceutical Service Innovation Competition and the Gold Award in the Pharmaceutical Management Group of the 4th China Hospital Management Awards in 2020); ② The construction of smart pharmacies increases efficiency while shortening outpatient waiting times, enhancing the outpatient experience (this project won the first prize in the 2023 Pharmaceutical Innovation Competition and the "Outstanding Case" award in the finals of the 8th Season of the National Hospital Competition for Improving Medical Services in the East China Region in 2023).
Academic status
National Health Commission of China Hospital Association Clinical Pharmacist Training Base (including specialized training in anti-infection, ICU, anti-tumor, neurology, nutrition, etc.)
Chinese Medical Association Clinical Pharmacist Training Base (including specialized training in cardiology and ICU)
Urgently Needed Talents - Pharmacist Position Training Program
Urgently Needed Talents – Clinical Pharmacist Training Program
National Level Training Courses on "Rational Drug Use and Clinical Practice of Pharmacists" and "PIVAS Pharmaceutical Services and Clinical Rational Drug Use"
Zhejiang Province Pretrial Center Pharmacist Training Base
Research achievements
To improve the safety and effectiveness of clinical drug use, the Department of Pharmacy conducts scientific research, particularly focusing on issues faced by patients related to clinical medication. The research directions include:
Designing and developing drug delivery systems with safety, high efficiency, targeting, and environmental responsiveness to address the issue of drugs.
Providing individualized dosing regimens and therapeutic drug monitoring strategies based on pharmacokinetics and pharmacodynamics principles to address the issue of large variability in drug response among patients.
Exploring the pathogenesis of diseases such as epilepsy, cerebral ischemia, and trigeminal neuralgia, analyzing the mechanisms of drug action and disease resistance to provide new strategies and targets for disease treatment.
Conducting innovative clinical comprehensive evaluations of drugs through pharmacovigilance research, pharmacoeconomics research, and pharmacoepidemiology research to provide evidence support and reference for hospital drug selection and rational drug use.
The department has hosted 4 projects funded by the National Natural Science Foundation, more than 20 provincial natural science foundation and provincial projects, and obtained more than 20 national invention patents. In recent years, the department has published over 100 high-quality and high-level papers, with 6 papers having an impact factor of 10 or above, the highest IF of 16.744. Representative achievements include a multicenter retrospective study led by Dr. YU Zhenwei and others, which first confirmed that tigecycline can cause drug-induced liver injury, clarified its incidence (10.3%) and risk factors (including abnormal baseline ALT levels, ICU admission, and long-term drug treatment), providing important guidance for the clinical application of tigecycline.