The SRRSH Department of Obstetrics and Gynecology & Reproductive Medicine Center encompasses gynecology, obstetrics, reproductive medicine, and neonatology. It is home to the Key Laboratory for Diagnosis and Treatment of Reproductive Disorders in Zhejiang Province and the Clinical Medical Research Center for Women's Diseases (Reproductive Disorders) in Zhejiang Province. The department is a key discipline in Zhejiang Province, a guidance center for minimally invasive reproductive techniques, one of the first national clinical research institutions for stem cells, a lead unit for key projects under the National Key Research and Development Program, and the Chair Unit of the Reproductive Medicine Branch of the Medical Association of Zhejiang Province. Currently, there are 133 doctors, including 26 with senior titles, 4 doctoral supervisors, 8 master's supervisors, and 171 specialized nurses. The department boasts a team of experienced experts in gynecology, obstetrics, reproductive medicine, and neonatology. They provide the most appropriate treatments for benign and malignant lesions in the female reproductive system, such as gynecological tumors, general gynecology, hysteroscopy, and gynecological endocrine diseases. They can accurately and promptly respond to normal pregnancy and childbirth, labor pain relief, various abnormal pregnancies, and obstetric emergencies. The Reproductive Medicine Center regularly conducts various assisted reproductive technologies, including artificial insemination and in vitro fertilization (IVF), with advanced techniques and leading success rates. Many couples from within and outside the province, as well as overseas, come for treatment. All the staff members of the Department of Reproductive Medicine Center & Obstetrics and Gynecology work together with dedication, striving to solve the pain of diseases for patients with gynecological, obstetric, and infertility issues using their expertise, solid theoretical knowledge, and enthusiasm at work.

Gynecology 

Our hospital's Gynecology specialty routinely performs various surgeries, including laparoscopy, hysteroscopy, open abdominal surgery, and colposcopy, providing the most appropriate treatments for all kinds of benign and malignant lesions in the female reproductive system, with an average annual surgical volume exceeding 10,000 cases. Currently, we have developed specialties such as robot-assisted (da Vinci) surgery for malignant gynecological tumors, single-port laparoscopic surgery for benign gynecological tumors, and one-day hysteroscopic diagnosis and treatment. Our department has always adhered to the concept of "fertility preservation", pioneering surgeries such as ovarian branch artery-preserving salpingectomy, cold knife sharp dissection of intrauterine adhesions under hysteroscopy to protect the endometrium, ovarian function-preserving surgery for endometriosis, and myomectomy to improve pregnancy rates, offering new opportunities for many infertile women. We have also conducted multiple national and provincial laparoscopy training sessions, making significant contributions to the development and popularization of laparoscopic technology in hospitals across the country. We became one of the first national training bases for fourth-grade gynecological laparoscopic surgery, and in 2011, our minimally invasive reproductive surgery specialty was recognized as an innovative discipline by the Health Department of Zhejiang Province.

Obstetrics 

The SRRSH Obstetrics specialty is the Zhejiang Provincial Critical Maternal Care Center and a national model institution for maternal and child safety. It is home to the Zhejiang Provincial Prenatal Diagnosis Center. With a team of experienced expert doctors, the specialty offers 86 mother-baby shared rooms, with an annual delivery volume of about 5,000. Available specialized services include high-risk obstetrics, fetal medicine, genetic counseling, cervical insufficiency, postpartum pelvic floor rehabilitation, recurrent miscarriage, neonatal diagnosis and care, and breastfeeding consultation. It provides single-room delivery suites and humanized services such as painless delivery and doula-supported childbirth. Leveraging the comprehensive multidisciplinary strengths of SRRSH, the specialty collaborates with departments such as Critical Care Medicine, Anesthesiology, Pulmonary and Critical Care Medicine, Cardiology, Thoracic Surgery, and Neurosurgery to form a joint treatment team, significantly improving the survival rate of critically ill pregnant women. Each year, it treats approximately 2,000 critically ill cases, including about 200 extremely severe cases. The Prenatal Diagnosis Center at SRRSH integrates outpatient clinics for fetal medicine and genetic counseling, interventional operating rooms, cytogenetic laboratories, ultrasound departments, and imaging departments. Services provided include:

1. Interventional prenatal diagnosis: Amniotic fluid and umbilical cord blood chromosome testing, BoBs rapid prenatal testing, chromosomal microarray analysis, whole-genome sequencing, etc.

2. Prenatal screening: NIPT, NIPT-P, NT examination, systematic fetal ultrasound, fetal echocardiography, fetal MRI, etc.

3. Fetal intrauterine treatment: Selective reduction, amniocentesis for drainage, fetal cyst aspiration, intrauterine treatment for fetal supraventricular tachycardia, etc. Through multidisciplinary consultations, the center provides guidance and prognosis assessment for high-risk pregnant women regarding eugenics, genetic diseases, adverse reproductive history, and medication use during pregnancy. It also offers prenatal diagnosis, intrauterine intervention, and prognosis assessment for fetuses with developmental abnormalities, as well as prenatal monitoring and postnatal follow-up treatment for ongoing pregnancies.

Neonatology 

The SRRSH Neonatology specialty is the Zhejiang Provincial Critical Neonatal Care Center. It has 48 beds equipped with 25 high-frequency ventilators, non-invasive ventilators, and a full set of intensive care equipment for newborns. The medical staff is highly skilled, and physicians at all levels can proficiently perform resuscitation for asphyxia. The department leads the country in the rescue of critically ill newborns, and management of nutrition and respiration in premature infants, with a survival rate for extremely premature infants reaching the national leading level. The lowest gestational age of successfully rescued infants is 24+1 weeks, and the lowest birth weight is 600 grams.

Reproductive Medicine Center 

The Reproductive Medicine Center routinely conducts first, second, and third-generation IVF and other assisted reproductive technologies, with over 8,000 egg retrieval cycles and more than 7,000 frozen-thawed embryo transfer cycles annually, maintaining stable pregnancy rates.

The Reproductive Health and Infertility specialty at SRRSH was established in 1998. SRRSH was among the first comprehensive hospitals in China to implement assisted reproductive technology, achieving Zhejiang Province's first IVF birth through intracytoplasmic sperm injection. Recognized as a national clinical key specialty and a leader in R&D initiatives, the center has been designated as the Zhejiang Center for Fertility Maintenance and Promotion, Zhejiang Center for Reproductive Minimally Invasive Techniques, and serves on various national and regional reproductive medicine committees. The center also hosts multiple innovation platforms, including the Zhejiang Reproductive Health Diseases Clinical Research Center and the Provincial Key Laboratory for Precision Fertility Protection and Promotion.

The team comprises 67 clinical physicians and six PI assistants, with 29.7% of them holding doctoral degrees, 68.9% with master’s degrees, 21 embryologists and specialized technicians, 22 reproductive nurses, and 10 physician assistants. Notably, the team includes a recipient of the National Outstanding Youth Fund, a “Ten Thousand Talents” youth expert, and five adjunct professors. The center encompasses subunits for female and male reproductive health, reproductive genetics, minimally invasive reproductive techniques, and foundational reproductive research. It has excelled in fertility preservation, reproductive organ reconstruction, male reproductive health, and complex reproductive disorders.

Under Prof. ZHANG Songying's leadership, the center consistently ranks at the top nationally in assisted reproductive cycles and success rates, attracting over 700,000 patients and performing more than 40,000 assisted reproductive procedures annually. The clinical pregnancy rates exceed 65% for fresh embryo transfers, 60% for frozen transfers, and 65% for preimplantation genetic testing, with high success rates in artificial insemination using both husband and donor sperm.

The center is a pioneer in reproductive minimally invasive techniques and spearheaded the writing of Chinese Expert Consensus on Diagnosis and Treatment of Tubal Infertility, a standardizing treatment practice nationwide. Its innovations include tension-free suturing in ectopic pregnancies, which markedly improves full-term pregnancy outcomes, as well as advancements in uterine isthmus cerclage to enhance full-term birth rates and neonatal quality which earned international recognition. Additionally, the center has introduced cold-knife techniques for intrauterine adhesiolysis and myomectomy under hysteroscopy. The department’s contributions to Technological Innovations to Enhance Assisted Reproductive Treatment Efficiency and Improve Birth Outcomes were honored with the 2020 Zhejiang Provincial Science and Technology Progress Award (First Class).

In fertility preservation, SRRSH pioneered stem cell-collagen compound techniques for thin endometrium repair and stem cell ovarian injections for premature ovarian failure, establishing international leadership in these areas. Ongoing research has been conducted on complex reproductive disorders, such as oocyte maturation and fertilization issues, integrating clinical insights to optimize assisted reproductive treatment outcomes. In 2020, Professor SUN Fei founded Zhejiang's first Center for Male Reproductive and Sexual Medicine, significantly advancing male reproductive health research and treatment.

Medical care services provided by the center include:

1. Artificial Insemination with Husband's Sperm (AIH) and Artificial Insemination with Donor Sperm (AID)

2. In Vitro Fertilization-Embryo Transfer (IVF-ET)

3. Donor Sperm IVF-ET

4. Intracytoplasmic Sperm Injection-Embryo Transfer (ICSI-ET) and Oocyte Activation

5. Microsurgical Sperm Retrieval, Percutaneous Testicular or Epididymal Sperm Aspiration

6. Preimplantation Genetic Testing for Aneuploidy (PGT-A)

7. Preimplantation Genetic Diagnosis for Chromosomal Structural

8. Abnormalities and Monogenic Diseases (PGT-SR & PGT-M)

9. Embryo Cryopreservation and Frozen-Thawed Embryo Transfer

10. Blastocyst Culture, Blastocyst Freezing, and Blastocyst Transfer

11. Assisted Hatching (AH)

12. Fetal Reduction for Multiple Pregnancies

13. Diagnosis and Treatment of Recurrent Miscarriage

14. Oocyte Cryopreservation for Medical Indications, and Ovarian Tissue 15. Cryopreservation and Transplantation for Patients with Benign or Malignant Tumors

16. Laparoscopic and Hysteroscopic Minimally Invasive Reproductive Surgery for Infertility, and Modified Uterine Isthmic Cerclage for Cervical Insufficiency (via Transvaginal and Laparoscopic Cerclage)

17. Follicle Monitoring, Ovulation Induction Treatment, and Diagnosis and Treatment of Gynecological and Reproductive Endocrine Disorders, such as Polycystic Ovary Syndrome (PCOS), Poor Ovarian Reserve, and Dysfunctional Uterine Bleeding

18. Routine + Strict Morphological Analysis, Sperm DNA Fragmentation Testing, Seminal Plasma Biochemical Analysis, and Sperm Cryopreservation

Education and training

We were the first in the country to offer simulation-based training courses for gynecological endoscopic surgery. We accept numerous physicians from inside and outside the province for further training, regularly hold continuing education seminars, conduct regional lectures on reproductive endocrinology and minimally invasive reproductive basics, and provide simulation training for hysteroscopy in regional hospitals, continuously enhancing the standardized diagnostic and treatment capabilities, clinical skills, and research innovation abilities of professionals in related fields across our province and even the country. Each year, we train nearly 100 high-quality specialists through various channels, including internships for medical students, undergraduate admissions, graduate admissions, doctoral admissions, standardized training for resident physicians, and specialized physician further training.

Location

Qingchun Outpatient Clinic: South Area and West Area of the 1st Floor, Tower 1; 22nd Floor, Tower 3 (Reproductive Medicine Center)

Qingchun Inpatient Ward: 5th Floor, Tower 2 (Gynecology); 6th Floor, Tower 2 (Gynecology)

Qiantang Outpatient Clinic: Zone 2, 2nd Floor, Tower 6 (Gynecology and Obstetrics)

Qiantang Inpatient Ward: 7th Floor, Tower 6 (Obstetrics); 8th Floor, Tower 6 (Obstetrics); West Area, 22nd Floor, Tower 6 (Gynecology); Neonatal Intensive Care Unit, 8th Floor, Tower 6 Phone: (0571) 86006667

Obstetrics and Gynecology

The department focuses on "minimally invasive" and "fertility preservation", applying these concepts comprehensively to all fields of obstetrics and gynecology, including general gynecology, gynecological tumors, uterine cavity lesions, female infertility, and recurrent miscarriage. Currently, the department’s minimally invasive technology is advanced domestically and at a leading position in the province, making it an important exchange center and training base for minimally invasive technology in China, with distinctive features in the international field of minimally invasive medicine.

Domestic Leading Technologies:

1. First successful pregnancy and delivery after hormone therapy for endometrioid adenocarcinoma followed by in vitro fertilization-embryo transfer.

2. First live birth without complications after laparoscopic management of combined horn pregnancy.

3. Modified vaginal cerclage for recurrent miscarriage.

4. Protection of the endometrium during hysteroscopic adhesion separation.

5. Laparoscopic core resection of fallopian tubes.

6. Management of complex and special location ectopic pregnancies via laparoscopy.

7. Preparation of the endometrium and pregnancy rates after frozen-thawed embryo transfer.

8. Laparoscopic tubal recanalization for tubal recanalization treatment.

9. Hysteroscopic repair of cesarean section scar defects.

Provincial Leading Technologies:

1. Various laparoscopic surgeries, such as ovarian, tubal, and uterine surgeries, with emphasis on fertility preservation.

2. Robot-assisted surgery for cervical cancer, endometrial cancer, and other benign and malignant gynecological tumors.

3. Single-port laparoscopic management of benign gynecological tumors.

4. One-day hysteroscopic diagnosis and treatment of various uterine cavity diseases.

5. Laparoscopic myomectomy and adenomyoma lesion excision (difficult cases).

6. Laparoscopic excision of deep pelvic endometriosis.

7. Various hysterectomies, including radical hysterectomy and pelvic lymphadenectomy.

8. Laparoscopic treatment of pelvic organ prolapse.

9. Comprehensive diagnosis and treatment of cervical diseases combining cervical cytology, HPV testing, colposcopy, and LEEP surgery.

Specialty Medical Services

1. Comprehensive treatment system combining minimally invasive gynecology and assisted reproductive technology.

2. Robot-assisted surgery for cervical cancer, endometrial cancer, and other benign and malignant gynecological tumors.

3. Single-port laparoscopic management of benign gynecological tumors.

4. Comprehensive diagnosis and treatment of various minimally invasive gynecological surgeries and gynecological tumors.

5. High-risk obstetrics and non-invasive prenatal DNA testing.

6. Modified vaginal cerclage for recurrent miscarriage.

7. Individualized comprehensive treatment for infertility combined with ovarian endometriotic cysts and decreased ovarian reserve, including laparoscopic cyst fenestration and electrocautery.

8. Laparoscopic core resection of fallopian tubes for patients requiring salpingectomy to reduce the impact on ovarian blood supply and lower the risk of ectopic pregnancy after embryo transfer.

9. Cold knife sharp dissection for severe intrauterine adhesions to minimize endometrial trauma.

10. Comprehensive planning for myomectomy, suturing, and postoperative pregnancy intervals in women who wish to conceive.

11. Formulation of endometrial preparation protocols and standards for frozen-thawed embryo transfer.

12. Successful pregnancy and delivery after hormone therapy for endometrioid adenocarcinoma followed by in vitro fertilization-embryo transfer.

13. Laparoscopic surgery for cervical cancer, endometrial cancer, and uterine sarcoma.

14. Laparoscopic treatment of complications from minimally invasive surgery, such as bladder fistula, ureteral fistula, and bowel fistula.

15. Hysteroscopic and laparoscopic diagnosis and treatment of ectopic pregnancies in various special locations and complex cases.

16. Standardized diagnosis and treatment of cervical diseases combining cervical cytology, HPV testing, and colposcopy.

17. Laparoscopic treatment of pelvic organ prolapse.

18. Laparoscopic tubal recanalization.

19. Hysteroscopic repair of cesarean section scar defects.

20. Comprehensive management of pregnancy complications and high-risk pregnancies, such as gestational diabetes and hypertensive disorders of pregnancy.

Reproductive Medicine Center

1. First Case in China of Pregnancy and Delivery for a Patient with Endometrioid Adenocarcinoma via IVF-ET following Progestin Therapy

2. World’s First Case of Continued Intrauterine Pregnancy and Full-Term Delivery after Embryo Extraction from Interstitial Pregnancy via Uterine Incision

3. Cold-Knife Adhesiolysis Technique for Comprehensive Treatment of Intrauterine Adhesions

4. Cold-Knife Hysteroscopic Myomectomy for Uterine Fibroids

5. Embryo Extraction with Tension-Free Suturing for Interstitial Pregnancy

6. Modified Uterine Isthmic Cerclage Technique

7. Laparoscopic Uterine Isthmic Cerclage

8. Fertility-Preserving Surgery for Gynecological Tumors

9. Microsurgical Sperm Retrieval

10. Cryopreservation Technique for Rare/Singular Sperm

11. Oocyte Cryopreservation, Ovarian Tissue Cryopreservation, and Transplantation

12. Blastocyst Biopsy and Preimplantation Genetic Testing Techniques

13. Individualized Endometrial Preparation and Frozen-Thawed Embryo Transfer Techniques

14. Stem Cell-Composite Collagen Repair for Thin Endometrium

15. Stem Cell Ovarian Injection Therapy for Premature Ovarian FailureAcademic status

Zhejiang Reproductive Health Disease Clinical Research Center

Zhejiang Center for Fertility Maintenance and Promotion

First Institution in China to Launch Gynecological Laparoscopy Training Courses Based on Simulation Models

National standardized training base for resident physicians and key professional training base in Zhejiang Province

One of the first national training bases for fourth-grade gynecological endoscopic surgery

Zhejiang Provincial Guidance Center for Minimally Invasive Reproductive Techniques

Key Laboratory for Diagnosis and Treatment of Reproductive Disorders in Zhejiang Province

Clinical Medical Research Center for Women's Diseases (Reproductive Disorders) in Zhejiang Province

Key discipline in Zhejiang Province

Guidance center for minimally invasive reproductive techniques

One of the first national clinical research institutions for stem cells

Lead unit for key projects under the National Key Research and Development Program

Chair Unit of the Reproductive Medicine Branch of the Medical Association of Zhejiang Province

Obstetrics and Gynecology

The department has undertaken one major project under the National Key Research and Development Program, over 20 projects funded by the National Natural Science Foundation, more than 30 projects funded by provincial and ministerial-level grants, and over 50 projects funded by municipal and departmental-level funds. It has published over 120 academic papers, including more than 90 SCI papers; obtained 3 national authorized invention patents and 2 utility model patents; edited one book on obstetrics and gynecology and co-edited another; and led or co-authored 8 Chinese expert consensus documents. The research results have won the First Prize and Second Prize of Scientific and Technological Progress in Zhejiang Province and the First Prize of Medical and Health Science and Technology in Zhejiang Province.

Research Directions

Technical Research Directions:

1. Minimally invasive reproductive surgery and fertility preservation.

2. Improved vaginal cerclage for recurrent miscarriage due to cervical insufficiency.

3. Surgical methods and anti-adhesion research for uterine adhesions.

4. Early diagnosis and surgical treatment of gynecological malignancies using hysteroscopy and laparoscopy.

5. Development of gynecological endoscopic surgical instruments.

Scientific Research Directions:

1. Functional disorders of reproductive organs and reshaping of fertility.

2. Gene screening and pathogenesis research of genetic diseases.

3. Molecular mechanism research of oocyte and early embryo development.

4. Mother-fetus interface molecular dialogue research on embryo implantation and placental development.

5. Pathogenesis and early diagnosis of gynecological malignancies.

6. Pathogenesis and treatment of infertility associated with endometriosis.

Reproductive Medicine Center

As a leading institution, the center has secured one National Key R&D Program project, two Regional Innovation Key Projects funded by the National Natural Science Foundation of China (NSFC), over 40 NSFC international cooperation and general youth projects, and numerous major provincial and ministerial projects. The team has published more than 100 SCI papers in prestigious journals such as Science Advances, Nucleic Acids Research, Nature Communications, Redox Biology, EMBO Journal, Nano Letters, Small, American Journal of Human Genetics, and Human Molecular Genetics. In 2020, it received the First-Class Zhejiang Provincial Science and Technology Progress Award.